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Osteoporosis of the vertebra and osteochondral remodeling of the endplate causes intervertebral disc degeneration in ovariectomized mice

BACKGROUND: Studies on the relationship between osteoporosis and intervertebral disc degeneration (IVDD) are inconsistent. Therefore, we assessed whether IVDD is affected by vertebral osteoporosis in ovariectomized mice and investigated the underlying pathogenesis of IVDD related to osteoporosis. ME...

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Detalles Bibliográficos
Autores principales: Xiao, Zhi-feng, He, Jian-bo, Su, Guo-yi, Chen, Mei-hui, Hou, Yu, Chen, Shu-dong, Lin, Ding-kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131954/
https://www.ncbi.nlm.nih.gov/pubmed/30201052
http://dx.doi.org/10.1186/s13075-018-1701-1