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Glial Cell Line-Derived Neurotrophic Factor (GDNF) Promotes Angiogenesis through the Demethylation of the Fibromodulin (FMOD) Promoter in Glioblastoma

BACKGROUND: Angiogenesis plays an important role in the progression of glioblastoma, with a high degree of malignancy. Previous studies have proved that glial cell line-derived neurotrophic factor (GDNF) and fibromodulin (FMOD) are strongly expressed in human glioblastoma. The purpose of this study...

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Detalles Bibliográficos
Autores principales: Chen, Maohua, Ba, Huajun, Lu, Chuan, Dai, Junxia, Sun, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131978/
https://www.ncbi.nlm.nih.gov/pubmed/30176167
http://dx.doi.org/10.12659/MSM.911669