APOBEC3B Activity Is Prevalent in Urothelial Carcinoma Cells and Only Slightly Affected by LINE-1 Expression

The most common mutational signature in urothelial carcinoma (UC), the most common type of urinary bladder cancer is assumed to be caused by the misdirected activity of APOBEC3 (A3) cytidine deaminases, especially A3A or A3B, which are known to normally restrict the propagation of exogenous viruses...

Descripción completa

Detalles Bibliográficos
Autores principales: Jaguva Vasudevan, Ananda Ayyappan, Kreimer, Ulrike, Schulz, Wolfgang A., Krikoni, Aikaterini, Schumann, Gerald G., Häussinger, Dieter, Münk, Carsten, Goering, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132077/
https://www.ncbi.nlm.nih.gov/pubmed/30233553
http://dx.doi.org/10.3389/fmicb.2018.02088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132077/
https://www.ncbi.nlm.nih.gov/pubmed/30233553
http://dx.doi.org/10.3389/fmicb.2018.02088

Ejemplares similares