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Constitutive activity of transient receptor potential vanilloid type 1 triggers spontaneous firing in nerve growth factor-treated dorsal root ganglion neurons of rats

Dorsal root ganglion (DRG) neurons cultured in the presence of nerve growth factor (NGF, 100 ng/ml) often show a spontaneous action potential. Underlying mechanisms of this spontaneous firing were examined using the patch clamp technique. The spontaneous firing in the on-cell configuration was aboli...

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Detalles Bibliográficos
Autores principales: Kitamura, Naoki, Nagami, Erika, Matsushita, Yumi, Kayano, Tomohiko, Shibuya, Izumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132080/
https://www.ncbi.nlm.nih.gov/pubmed/30211336
http://dx.doi.org/10.1016/j.ibror.2018.08.002