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Dabrafenib and Trametinib Treatment for Erdheim-Chester Disease With Brain Stem Involvement

Erdheim-Chester disease (ECD) is a rare form of non–Langerhans cell histiocytosis characterized by infiltration of organs by CD68(+) and CD1a(−) lipid-laden histiocytes, including the central nervous system in more than a third of patients. Molecular analysis of ECD samples has demonstrated the prev...

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Detalles Bibliográficos
Autores principales: Al Bayati, Ahmed, Plate, Thomas, Al Bayati, Mahmood, Yan, Yaohong, Lavi, Efrat Saraf, Rosenblatt, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132217/
https://www.ncbi.nlm.nih.gov/pubmed/30225465
http://dx.doi.org/10.1016/j.mayocpiqo.2018.05.001