Cargando…

PAX5A and PAX5B isoforms are both efficient to drive B cell differentiation

Pax5 is the guardian of the B cell identity since it primes or enhances the expression of B cell specific genes and concomitantly represses the expression of B cell inappropriate genes. The tight regulation of Pax5 is therefore required for an efficient B cell differentiation. A defect in its dosage...

Descripción completa

Detalles Bibliográficos
Autores principales: Cresson, Charlotte, Péron, Sophie, Jamrog, Laura, Rouquié, Nelly, Prade, Nais, Dubois, Marine, Hébrard, Sylvie, Lagarde, Stéphanie, Gerby, Bastien, Mancini, Stéphane J.C., Cogné, Michel, Delabesse, Eric, Delpy, Laurent, Broccardo, Cyril
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132355/
https://www.ncbi.nlm.nih.gov/pubmed/30214688
http://dx.doi.org/10.18632/oncotarget.26003