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PAX5A and PAX5B isoforms are both efficient to drive B cell differentiation
Pax5 is the guardian of the B cell identity since it primes or enhances the expression of B cell specific genes and concomitantly represses the expression of B cell inappropriate genes. The tight regulation of Pax5 is therefore required for an efficient B cell differentiation. A defect in its dosage...
Autores principales: | Cresson, Charlotte, Péron, Sophie, Jamrog, Laura, Rouquié, Nelly, Prade, Nais, Dubois, Marine, Hébrard, Sylvie, Lagarde, Stéphanie, Gerby, Bastien, Mancini, Stéphane J.C., Cogné, Michel, Delabesse, Eric, Delpy, Laurent, Broccardo, Cyril |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132355/ https://www.ncbi.nlm.nih.gov/pubmed/30214688 http://dx.doi.org/10.18632/oncotarget.26003 |
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