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Population pharmacokinetics of levodopa/carbidopa microtablets in healthy subjects and Parkinson’s disease patients

OBJECTIVES: Low dose, dispersible, levodopa/carbidopa microtablets with an automatic dose dispenser have been developed to facilitate individualized levodopa treatment. The aim of this study was to characterize the pharmacokinetics (PK) of levodopa and carbidopa after microtablet administration, and...

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Detalles Bibliográficos
Autores principales: Senek, Marina, Nyholm, Dag, Nielsen, Elisabet I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132549/
https://www.ncbi.nlm.nih.gov/pubmed/29882153
http://dx.doi.org/10.1007/s00228-018-2497-2