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Molecular basis of atypicality of bupropion inferred from its receptor engagement in nervous system tissues

Despite decades of clinical use and research, the mechanism of action (MOA) of antidepressant medications remains poorly understood. Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) are the most commonly prescribed antidepressants—atypical anti...

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Detalles Bibliográficos
Autores principales: Kim, Eric J., Felsovalyi, Klara, Young, Lauren M., Shmelkov, Sergey V., Grunebaum, Michael F., Cardozo, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132670/
https://www.ncbi.nlm.nih.gov/pubmed/29961917
http://dx.doi.org/10.1007/s00213-018-4958-9