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Current knowledge and recent insights into the genetic basis of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is the most frequent motor neuron disease, affecting the upper and/or lower motor neurons. However, extramotor symptoms can also occur; cognitive deficits are present in more than 40% of patients and 5–8% of ALS patients develop frontotemporal dementia. There is n...

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Detalles Bibliográficos
Autores principales: Volk, Alexander E., Weishaupt, Jochen H., Andersen, Peter M., Ludolph, Albert C., Kubisch, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132774/
https://www.ncbi.nlm.nih.gov/pubmed/30220791
http://dx.doi.org/10.1007/s11825-018-0185-3