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d-ribose induces nephropathy through RAGE-dependent NF-κB inflammation

Recently, aberrantly high levels of d-ribose have been discovered in type II diabetic patients. d-ribose glycates proteins more rapidly than d-glucose, resulting in the production of advanced glycation end products (AGEs). Accumulations of these products can be found in impaired renal function, but...

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Detalles Bibliográficos
Autores principales: Hong, Jinni, Wang, Xuemei, Zhang, Ning, Fu, Hong, Li, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pharmaceutical Society of Korea 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132794/
https://www.ncbi.nlm.nih.gov/pubmed/30101366
http://dx.doi.org/10.1007/s12272-018-1061-z