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A phase 1 dose-escalation study on the safety, tolerability and activity of liposomal curcumin (Lipocurc(™)) in patients with locally advanced or metastatic cancer

PURPOSE: This study was conducted to investigate the safety and tolerability of increasing doses of liposomal curcumin in patients with metastatic cancer. Investigations of anti-tumor activity and of the pharmacokinetics of curcumin were secondary objectives. METHODS: In this phase I, single-center,...

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Detalles Bibliográficos
Autores principales: Greil, Richard, Greil-Ressler, Sigrun, Weiss, Lukas, Schönlieb, Charlotte, Magnes, Teresa, Radl, Bianca, Bolger, Gordon T., Vcelar, Brigitta, Sordillo, Peter P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132848/
https://www.ncbi.nlm.nih.gov/pubmed/30074076
http://dx.doi.org/10.1007/s00280-018-3654-0