CD11c(+) MHCII(lo) GM-CSF-bone marrow-derived dendritic cells act as antigen donor cells and as antigen presenting cells in neoepitope-elicited tumor immunity against a mouse fibrosarcoma

Dendritic cells play a critical role in initiating T-cell responses. In spite of this recognition, they have not been used widely as adjuvants, nor is the mechanism of their adjuvanticity fully understood. Here, using a mutated neoepitope of a mouse fibrosarcoma as the antigen, and tumor rejection a...

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Detalles Bibliográficos
Autores principales: Ebrahimi-Nik, Hakimeh, Corwin, William L., Shcheglova, Tatiana, Das Mohapatra, Alok, Mandoiu, Ion I., Srivastava, Pramod K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132860/
https://www.ncbi.nlm.nih.gov/pubmed/30030558
http://dx.doi.org/10.1007/s00262-018-2202-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132860/
https://www.ncbi.nlm.nih.gov/pubmed/30030558
http://dx.doi.org/10.1007/s00262-018-2202-4

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