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Determination of Puquitinib in Human Plasma by HPLC–ESI MS/MS: Application to Pharmacokinetic Study

BACKGROUND AND OBJECTIVE: Puquitinib mesylate (XC-302) is a new multiple-target anticancer inhibitor, which directly suppresses the activity of phosphatidylinositol 3-kinase (PI3K). This study was aimed to develop a sensitive and specific liquid chromatography electrospray ionization tandem mass spe...

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Detalles Bibliográficos
Autores principales: Zhan, Jing, Ding, Ya, Zou, Benyan, Liao, Hai, Jiang, Wenqi, Li, Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133078/
https://www.ncbi.nlm.nih.gov/pubmed/29520719
http://dx.doi.org/10.1007/s13318-018-0468-8