Synthesis of 2-alkylthio-N-(quinazolin-2-yl)benzenesulfonamide derivatives: anticancer activity, QSAR studies, and metabolic stability

ABSTRACT: A new series of 2-alkylthio-N-(quinazolin-2-yl)benzenesulfonamide derivatives have been synthesized and evaluated in vitro for their antiproliferative activity by MTT assay against cancer cell lines HCT-116, MCF-7, and HeLa as well as the NCI-60 human tumor cell lines screen. In NCI screen...

Descripción completa

Detalles Bibliográficos
Autores principales: Pogorzelska, Aneta, Żołnowska, Beata, Sławiński, Jarosław, Kawiak, Anna, Szafrański, Krzysztof, Belka, Mariusz, Bączek, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133092/
https://www.ncbi.nlm.nih.gov/pubmed/30237621
http://dx.doi.org/10.1007/s00706-018-2251-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133092/
https://www.ncbi.nlm.nih.gov/pubmed/30237621
http://dx.doi.org/10.1007/s00706-018-2251-6

Ejemplares similares