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Synthesis of 2-alkylthio-N-(quinazolin-2-yl)benzenesulfonamide derivatives: anticancer activity, QSAR studies, and metabolic stability
ABSTRACT: A new series of 2-alkylthio-N-(quinazolin-2-yl)benzenesulfonamide derivatives have been synthesized and evaluated in vitro for their antiproliferative activity by MTT assay against cancer cell lines HCT-116, MCF-7, and HeLa as well as the NCI-60 human tumor cell lines screen. In NCI screen...
Autores principales: | Pogorzelska, Aneta, Żołnowska, Beata, Sławiński, Jarosław, Kawiak, Anna, Szafrański, Krzysztof, Belka, Mariusz, Bączek, Tomasz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133092/ https://www.ncbi.nlm.nih.gov/pubmed/30237621 http://dx.doi.org/10.1007/s00706-018-2251-6 |
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