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MANF protects human pancreatic beta cells against stress-induced cell death

AIMS/HYPOTHESIS: There is a great need to identify factors that could protect pancreatic beta cells against apoptosis or stimulate their replication and thus prevent or reverse the development of diabetes. One potential candidate is mesencephalic astrocyte-derived neurotrophic factor (MANF), an endo...

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Detalles Bibliográficos
Autores principales: Hakonen, Elina, Chandra, Vikash, Fogarty, Christopher L., Yu, Nancy Yiu-Lin, Ustinov, Jarkko, Katayama, Shintaro, Galli, Emilia, Danilova, Tatiana, Lindholm, Päivi, Vartiainen, Aki, Einarsdottir, Elisabet, Krjutškov, Kaarel, Kere, Juha, Saarma, Mart, Lindahl, Maria, Otonkoski, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133171/
https://www.ncbi.nlm.nih.gov/pubmed/30032427
http://dx.doi.org/10.1007/s00125-018-4687-y