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Abnormalities of Mitochondrial Dynamics in the Failing Heart: Normalization Following Long-Term Therapy with Elamipretide

PURPOSE: Abnormalities of MITO dynamics occur in HF and have been implicated in disease progression. This study describes the broad range abnormalities of mitochondrial (MITO) dynamics in Heart Failure with reduced ejection fraction (HF) and evaluates the effects of long-term therapy with elamipreti...

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Detalles Bibliográficos
Autores principales: Sabbah, Hani N., Gupta, Ramesh C., Singh-Gupta, Vinita, Zhang, Kefei, Lanfear, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133191/
https://www.ncbi.nlm.nih.gov/pubmed/29951944
http://dx.doi.org/10.1007/s10557-018-6805-y