DZ-2384 has a superior preclinical profile to taxanes for the treatment of triple-negative breast cancer and is synergistic with anti-CTLA-4 immunotherapy

Triple-negative breast cancer (TNBC) is typically aggressive, difficult to treat, and commonly metastasizes to the visceral organs and soft tissues, including the lungs and the brain. Taxanes represent the most effective and widely used therapeutic class in metastatic TNBC but possess limiting adver...

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Detalles Bibliográficos
Autores principales: Bernier, Cynthia, Soliman, Ahmed, Gravel, Michel, Dankner, Matthew, Savage, Paul, Petrecca, Kevin, Park, Morag, Siegel, Peter M., Shore, Gordon C., Roulston, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Preclinical Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133219/
https://www.ncbi.nlm.nih.gov/pubmed/29878901
http://dx.doi.org/10.1097/CAD.0000000000000653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133219/
https://www.ncbi.nlm.nih.gov/pubmed/29878901
http://dx.doi.org/10.1097/CAD.0000000000000653

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