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Performance of different clinical trial designs to evaluate treatments during an epidemic

In the 2013-2016 west Africa outbreak of Ebola Virus Disease (EVD), most of the planned clinical trials failed to reach a conclusion within the time frame of the epidemic. The performance of clinical trial designs for the evaluation of one or more experimental treatments in the specific context of a...

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Detalles Bibliográficos
Autores principales: Brueckner, Matthias, Titman, Andrew, Jaki, Thomas, Rojek, Amanda, Horby, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133355/
https://www.ncbi.nlm.nih.gov/pubmed/30204799
http://dx.doi.org/10.1371/journal.pone.0203387