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Donor-derived Cell-free DNA Identifies Antibody-mediated Rejection in Donor Specific Antibody Positive Kidney Transplant Recipients

BACKGROUND: Elevated levels of donor-derived cell-free DNA (dd-cfDNA) in the plasma of renal allograft recipients indicates organ injury and an increased probability of active rejection. Donor-specific antibodies (DSA) to HLA antigens are associated with risk of antibody-mediated rejection (ABMR). T...

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Detalles Bibliográficos
Autores principales: Jordan, Stanley C., Bunnapradist, Suphamai, Bromberg, Jonathan S., Langone, Anthony J., Hiller, David, Yee, James P., Sninsky, John J., Woodward, Robert N., Matas, Arthur J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133406/
https://www.ncbi.nlm.nih.gov/pubmed/30234148
http://dx.doi.org/10.1097/TXD.0000000000000821