Insights into the key determinants of membrane protein topology enable the identification of new monotopic folds

Monotopic membrane proteins integrate into the lipid bilayer via reentrant hydrophobic domains that enter and exit on a single face of the membrane. Whereas many membrane-spanning proteins have been structurally characterized and transmembrane topologies can be predicted computationally, relatively...

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Detalles Bibliográficos
Autores principales: Entova, Sonya, Billod, Jean-Marc, Swiecicki, Jean-Marie, Martín-Santamaría, Sonsoles, Imperiali, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133551/
https://www.ncbi.nlm.nih.gov/pubmed/30168796
http://dx.doi.org/10.7554/eLife.40889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133551/
https://www.ncbi.nlm.nih.gov/pubmed/30168796
http://dx.doi.org/10.7554/eLife.40889

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