STING agonist therapy in combination with PD-1 immune checkpoint blockade enhances response to carboplatin chemotherapy in high-grade serous ovarian cancer

BACKGROUND: High-grade serous carcinoma (HGSC) of the ovary is predominantly diagnosed at late stages and primarily treated with debulking surgery followed by platinum/taxane-based chemotherapy. Although certain patients benefit significantly from currently used chemotherapy, there are patients who...

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Detalles Bibliográficos
Autores principales: Ghaffari, Abdi, Peterson, Nichole, Khalaj, Kasra, Vitkin, Natasha, Robinson, Andrew, Francis, Julie-Ann, Koti, Madhuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133940/
https://www.ncbi.nlm.nih.gov/pubmed/30046165
http://dx.doi.org/10.1038/s41416-018-0188-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133940/
https://www.ncbi.nlm.nih.gov/pubmed/30046165
http://dx.doi.org/10.1038/s41416-018-0188-5

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