Phosphoproteomic-based kinase profiling early in influenza virus infection identifies GRK2 as antiviral drug target

Although annual influenza epidemics affect around 10% of the global population, current treatment options are limited and development of new antivirals is needed. Here, using quantitative phosphoproteomics, we reveal the unique phosphoproteome dynamics that occur in the host cell within minutes of i...

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Detalles Bibliográficos
Autores principales: Yángüez, Emilio, Hunziker, Annika, Dobay, Maria Pamela, Yildiz, Soner, Schading, Simon, Elshina, Elizaveta, Karakus, Umut, Gehrig, Peter, Grossmann, Jonas, Dijkman, Ronald, Schmolke, Mirco, Stertz, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133941/
https://www.ncbi.nlm.nih.gov/pubmed/30206219
http://dx.doi.org/10.1038/s41467-018-06119-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133941/
https://www.ncbi.nlm.nih.gov/pubmed/30206219
http://dx.doi.org/10.1038/s41467-018-06119-y

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