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Fra2 Overexpression in Mice Leads to Non-allergic Asthma Development in an IL-13 Dependent Manner

Background: Asthma is a complex chronic inflammatory disease characterised by airway inflammation, remodelling and hyperresponsiveness (AHR). Members of the AP-1 transcription factor family play important roles in the activation of the immune system and the control of cellular responses; however, th...

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Detalles Bibliográficos
Autores principales: Gungl, Anna, Biasin, Valentina, Wilhelm, Jochen, Olschewski, Andrea, Kwapiszewska, Grazyna, Marsh, Leigh M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133984/
https://www.ncbi.nlm.nih.gov/pubmed/30233597
http://dx.doi.org/10.3389/fimmu.2018.02018