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Glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin

Fosfazinomycin and kinamycin are natural products that contain nitrogen–nitrogen (N–N) bonds but that are otherwise structurally unrelated. Despite their considerable structural differences, their biosynthetic gene clusters share a set of genes predicted to facilitate N–N bond formation. In this stu...

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Detalles Bibliográficos
Autores principales: Wang, Kwo-Kwang A., Ng, Tai L., Wang, Peng, Huang, Zedu, Balskus, Emily P., van der Donk, Wilfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133997/
https://www.ncbi.nlm.nih.gov/pubmed/30206228
http://dx.doi.org/10.1038/s41467-018-06083-7