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Glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin
Fosfazinomycin and kinamycin are natural products that contain nitrogen–nitrogen (N–N) bonds but that are otherwise structurally unrelated. Despite their considerable structural differences, their biosynthetic gene clusters share a set of genes predicted to facilitate N–N bond formation. In this stu...
Autores principales: | Wang, Kwo-Kwang A., Ng, Tai L., Wang, Peng, Huang, Zedu, Balskus, Emily P., van der Donk, Wilfred A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133997/ https://www.ncbi.nlm.nih.gov/pubmed/30206228 http://dx.doi.org/10.1038/s41467-018-06083-7 |
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