ADAP1 limits neonatal cardiomyocyte hypertrophy by reducing integrin cell surface expression

The ArfGAP with dual PH domains 1 (ADAP1) regulates the activation of the hypertrophic mitogen-activated protein kinase ERK1/2 pathway in non-cardiomyocytes. However, its role in cardiomyocytes is unknown. Our aim was to characterize the role of ADAP1 in the hypertrophic process of cardiomyocytes. W...

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Detalles Bibliográficos
Autores principales: Giguère, Hugo, Dumont, Audrey-Ann, Berthiaume, Jonathan, Oliveira, Vanessa, Laberge, Gino, Auger-Messier, Mannix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134004/
https://www.ncbi.nlm.nih.gov/pubmed/30206251
http://dx.doi.org/10.1038/s41598-018-31784-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134004/
https://www.ncbi.nlm.nih.gov/pubmed/30206251
http://dx.doi.org/10.1038/s41598-018-31784-w

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