Cargando…
ADAP1 limits neonatal cardiomyocyte hypertrophy by reducing integrin cell surface expression
The ArfGAP with dual PH domains 1 (ADAP1) regulates the activation of the hypertrophic mitogen-activated protein kinase ERK1/2 pathway in non-cardiomyocytes. However, its role in cardiomyocytes is unknown. Our aim was to characterize the role of ADAP1 in the hypertrophic process of cardiomyocytes. W...
Autores principales: | Giguère, Hugo, Dumont, Audrey-Ann, Berthiaume, Jonathan, Oliveira, Vanessa, Laberge, Gino, Auger-Messier, Mannix |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134004/ https://www.ncbi.nlm.nih.gov/pubmed/30206251 http://dx.doi.org/10.1038/s41598-018-31784-w |
Ejemplares similares
-
Monitoring TRPC7 Conformational Changes by BRET Following GPCR Activation
por: Pétigny, Cécile, et al.
Publicado: (2022) -
Integrin Activation Through the Hematopoietic Adapter Molecule ADAP Regulates Dendritic Development of Hippocampal Neurons
por: Thiere, Marlen, et al.
Publicado: (2016) -
CIB1 is a Regulator of Pathological Cardiac Hypertrophy
por: Heineke, Joerg, et al.
Publicado: (2010) -
Ultrasensitive Antibody Detection by Agglutination-PCR
(ADAP)
por: Tsai, Cheng-ting, et al.
Publicado: (2016) -
The Immune Adaptor ADAP Regulates Reciprocal TGF-β1-Integrin Crosstalk to Protect from Influenza Virus Infection
por: Li, Chunyang, et al.
Publicado: (2015)