The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects

Genome instability is associated with tumorigenesis. Here, we identify a role for the histone Htz1, which is deposited by the Swr1 chromatin-remodeling complex (SWR-C), in preventing genome instability in the absence of the replication fork/replication checkpoint proteins Mrc1, Csm3, or Tof1. When c...

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Detalles Bibliográficos
Autores principales: Srivatsan, Anjana, Li, Bin-Zhong, Szakal, Barnabas, Branzei, Dana, Putnam, Christopher D., Kolodner, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134005/
https://www.ncbi.nlm.nih.gov/pubmed/30206225
http://dx.doi.org/10.1038/s41467-018-06131-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134005/
https://www.ncbi.nlm.nih.gov/pubmed/30206225
http://dx.doi.org/10.1038/s41467-018-06131-2

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