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Effects of dichloroacetate as single agent or in combination with GW6471 and metformin in paraganglioma cells

Paragangliomas (PGLs) are infiltrating autonomic nervous system tumors that cause important morbidity. At present, surgery is the only effective therapeutic option for this rare tumor. Thus, new agents for PGL treatment should be identified. Using unique PGL cell models established in our laboratory...

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Detalles Bibliográficos
Autores principales: Florio, Rosalba, De Lellis, Laura, Veschi, Serena, Verginelli, Fabio, di Giacomo, Viviana, Gallorini, Marialucia, Perconti, Silvia, Sanna, Mario, Mariani-Costantini, Renato, Natale, Angelica, Arduini, Arduino, Amoroso, Rosa, Cataldi, Amelia, Cama, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134030/
https://www.ncbi.nlm.nih.gov/pubmed/30206358
http://dx.doi.org/10.1038/s41598-018-31797-5