Cargando…

Phenotypic Basis for Matrix Stiffness-Dependent Chemoresistance of Breast Cancer Cells to Doxorubicin

The persistence of drug resistant cell populations following chemotherapeutic treatment is a significant challenge in the clinical management of cancer. Resistant subpopulations arise via both cell intrinsic and extrinsic mechanisms. Extrinsic factors in the microenvironment, including neighboring c...

Descripción completa

Detalles Bibliográficos
Autores principales: Joyce, M. Hunter, Lu, Carolyne, James, Emily R., Hegab, Rachel, Allen, Shane C., Suggs, Laura J., Brock, Amy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134055/
https://www.ncbi.nlm.nih.gov/pubmed/30234012
http://dx.doi.org/10.3389/fonc.2018.00337