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Phenotypic Basis for Matrix Stiffness-Dependent Chemoresistance of Breast Cancer Cells to Doxorubicin
The persistence of drug resistant cell populations following chemotherapeutic treatment is a significant challenge in the clinical management of cancer. Resistant subpopulations arise via both cell intrinsic and extrinsic mechanisms. Extrinsic factors in the microenvironment, including neighboring c...
Autores principales: | Joyce, M. Hunter, Lu, Carolyne, James, Emily R., Hegab, Rachel, Allen, Shane C., Suggs, Laura J., Brock, Amy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134055/ https://www.ncbi.nlm.nih.gov/pubmed/30234012 http://dx.doi.org/10.3389/fonc.2018.00337 |
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