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Chemogenetic Recruitment of Specific Interneurons Suppresses Seizure Activity

Current anti-epileptic medications that boost synaptic inhibition are effective in reducing several types of epileptic seizure activity. Nevertheless, these drugs can generate significant side-effects and even paradoxical responses due to the broad nature of their action. Recently developed chemogen...

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Detalles Bibliográficos
Autores principales: Cǎlin, Alexandru, Stancu, Mihai, Zagrean, Ana-Maria, Jefferys, John G. R., Ilie, Andrei S., Akerman, Colin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134067/
https://www.ncbi.nlm.nih.gov/pubmed/30233328
http://dx.doi.org/10.3389/fncel.2018.00293