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Candida albicans Hyphal Expansion Causes Phagosomal Membrane Damage and Luminal Alkalinization

Macrophages rely on phagosomal acidity to destroy engulfed microorganisms. To survive this hostile response, opportunistic fungi such as Candida albicans developed strategies to evade the acidic environment. C. albicans is polymorphic and able to convert from yeast to hyphae, and this transition is...

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Detalles Bibliográficos
Autores principales: Westman, Johannes, Moran, Gary, Mogavero, Selene, Hube, Bernhard, Grinstein, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134096/
https://www.ncbi.nlm.nih.gov/pubmed/30206168
http://dx.doi.org/10.1128/mBio.01226-18