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Transcriptional Regulation Buffers Gene Dosage Effects on a Highly Expressed Operon in Salmonella

Highly expressed genes are commonly located close to the origin of replication of bacterial chromosomes (OriC). This location skew is thought to reflect selective advantages associated with gene dosage effects during the replication cycle. The expression of constitutively expressed genes can vary up...

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Detalles Bibliográficos
Autores principales: Garmendia, Eva, Brandis, Gerrit, Hughes, Diarmaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134099/
https://www.ncbi.nlm.nih.gov/pubmed/30206172
http://dx.doi.org/10.1128/mBio.01446-18