KLLN-mediated DNA damage-induced apoptosis is associated with regulation of p53 phosphorylation and acetylation in breast cancer cells

KLLN is a target of p53 involved in S-phase cell cycle regulation deemed necessary and sufficient for p53-mediated apoptosis. Germline promoter hypermethylation of KLLN is associated with a cancer-predisposition syndrome, Cowden syndrome. KLLN’s DNA-binding ability is associated with transcription r...

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Detalles Bibliográficos
Autores principales: Sankunny, Madhav, Eng, Charis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134104/
https://www.ncbi.nlm.nih.gov/pubmed/30245854
http://dx.doi.org/10.1038/s41420-018-0094-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134104/
https://www.ncbi.nlm.nih.gov/pubmed/30245854
http://dx.doi.org/10.1038/s41420-018-0094-x

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