MicroRNA-128a represses chondrocyte autophagy and exacerbates knee osteoarthritis by disrupting Atg12

Chondrocyte loss is a prominent feature of osteoarthritis (OA). Autophagy is indispensable in maintaining the metabolic activities of cells exposed to deleterious stress. The contribution of microRNA signaling to chondrocyte autophagy in OA development remains elusive. We uncovered an association be...

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Detalles Bibliográficos
Autores principales: Lian, Wei-Shiung, Ko, Jih-Yang, Wu, Re-Weng, Sun, Yi-Chih, Chen, Yu-Shan, Wu, Shin-Long, Weng, Lin-Hsiu, Jahr, Holger, Wang, Feng-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134128/
https://www.ncbi.nlm.nih.gov/pubmed/30206206
http://dx.doi.org/10.1038/s41419-018-0994-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134128/
https://www.ncbi.nlm.nih.gov/pubmed/30206206
http://dx.doi.org/10.1038/s41419-018-0994-y

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