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MicroRNA-128a represses chondrocyte autophagy and exacerbates knee osteoarthritis by disrupting Atg12
Chondrocyte loss is a prominent feature of osteoarthritis (OA). Autophagy is indispensable in maintaining the metabolic activities of cells exposed to deleterious stress. The contribution of microRNA signaling to chondrocyte autophagy in OA development remains elusive. We uncovered an association be...
Autores principales: | Lian, Wei-Shiung, Ko, Jih-Yang, Wu, Re-Weng, Sun, Yi-Chih, Chen, Yu-Shan, Wu, Shin-Long, Weng, Lin-Hsiu, Jahr, Holger, Wang, Feng-Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134128/ https://www.ncbi.nlm.nih.gov/pubmed/30206206 http://dx.doi.org/10.1038/s41419-018-0994-y |
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