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GraphDDP: a graph-embedding approach to detect differentiation pathways in single-cell-data using prior class knowledge
Cell types can be characterized by expression profiles derived from single-cell RNA-seq. Subpopulations are identified via clustering, yielding intuitive outcomes that can be validated by marker genes. Clustering, however, implies a discretization that cannot capture the continuous nature of differe...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134144/ https://www.ncbi.nlm.nih.gov/pubmed/30206223 http://dx.doi.org/10.1038/s41467-018-05988-7 |