GWAS for Interleukin-1β levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation

There is no agnostic GWAS evidence for the genetic control of IL-1β expression in periodontal disease. Here we report a GWAS for “high” gingival crevicular fluid IL-1β expression among 4910 European-American adults and identify association signals in the IL37 locus. rs3811046 at this locus (p = 3.3 ...

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Detalles Bibliográficos
Autores principales: Offenbacher, Steven, Jiao, Yizu, Kim, Steven J., Marchesan, Julie, Moss, Kevin L., Jing, Li, Divaris, Kimon, Bencharit, Sompop, Agler, Cary S., Morelli, Thiago, Zhang, Shaoping, Sun, Lu, Seaman, William T., Cowley, Dale, Barros, Silvana P., Beck, James D., Munz, Matthias, Schaefer, Arne S., North, Kari E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134146/
https://www.ncbi.nlm.nih.gov/pubmed/30206230
http://dx.doi.org/10.1038/s41467-018-05940-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134146/
https://www.ncbi.nlm.nih.gov/pubmed/30206230
http://dx.doi.org/10.1038/s41467-018-05940-9

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