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Clinical Relevance of Genomic Changes in Recurrent Pediatric Solid Tumors
PURPOSE: Relapsed/refractory pediatric cancers show poor prognosis; however, their genomic patterns remain unknown. To investigate the genetic mechanisms of tumor relapse and therapy resistance, we characterized genomic alterations in diagnostic and relapsed lesions in patients with relapsed/refract...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134157/ https://www.ncbi.nlm.nih.gov/pubmed/30216764 http://dx.doi.org/10.1016/j.tranon.2018.08.013 |