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Clinical Relevance of Genomic Changes in Recurrent Pediatric Solid Tumors

PURPOSE: Relapsed/refractory pediatric cancers show poor prognosis; however, their genomic patterns remain unknown. To investigate the genetic mechanisms of tumor relapse and therapy resistance, we characterized genomic alterations in diagnostic and relapsed lesions in patients with relapsed/refract...

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Detalles Bibliográficos
Autores principales: Lee, Boram, Lee, Ji Won, Shim, Joon Ho, Joung, Je-Gun, Yun, Jae Won, Bae, Joon Seol, Shin, Hyun-Tae, Sung, Ki Woong, Park, Woong-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134157/
https://www.ncbi.nlm.nih.gov/pubmed/30216764
http://dx.doi.org/10.1016/j.tranon.2018.08.013

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