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Stage 2 Registered Report: Variation in neurodevelopmental outcomes in children with sex chromosome trisomies: testing the double hit hypothesis

Background: The presence of an extra sex chromosome is associated with an increased rate of neurodevelopmental difficulties involving language. The 'double hit' hypothesis proposes that the adverse impact of the extra sex chromosome is amplified when genes that are expressed from the sex c...

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Detalles Bibliográficos
Autores principales: Newbury, Dianne F., Simpson, Nuala H., Thompson, Paul A., Bishop, Dorothy V. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134338/
https://www.ncbi.nlm.nih.gov/pubmed/30271887
http://dx.doi.org/10.12688/wellcomeopenres.14677.4