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Screening Clinical Cell Products for Replication Competent Retrovirus: The National Gene Vector Biorepository Experience
Replication-competent retrovirus (RCR) is a safety concern for individuals treated with retroviral gene therapy. RCR detection assays are used to detect RCR in manufactured vector, transduced cell products infused into research subjects, and in the research subjects after treatment. In this study, w...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134358/ https://www.ncbi.nlm.nih.gov/pubmed/30211249 http://dx.doi.org/10.1016/j.omtm.2018.08.006 |