Screening Clinical Cell Products for Replication Competent Retrovirus: The National Gene Vector Biorepository Experience

Replication-competent retrovirus (RCR) is a safety concern for individuals treated with retroviral gene therapy. RCR detection assays are used to detect RCR in manufactured vector, transduced cell products infused into research subjects, and in the research subjects after treatment. In this study, w...

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Detalles Bibliográficos
Autores principales: Cornetta, Kenneth, Duffy, Lisa, Feldman, Steven A., Mackall, Crystal L., Davila, Marco L., Curran, Kevin J., Junghans, Richard P., Tang, Jean Yuh, Kochenderfer, James N., O’Cearbhaill, Roisin, Archer, Gary, Kiem, Hans-Peter, Shah, Nirali N., Delbrook, Cindy, Kaplan, Rosie, Brentjens, Renier J., Rivière, Isabelle, Sadelain, Michel, Rosenberg, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134358/
https://www.ncbi.nlm.nih.gov/pubmed/30211249
http://dx.doi.org/10.1016/j.omtm.2018.08.006

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