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Downregulation of Matrix Metalloproteinases 2 and 9 is Involved in the Protective Effect of Trehalose on Spinal Cord Injury

Upregulation of matrix metalloproteinases (MMPs), in particular MMP-2 and MMP-9 contributes to secondary pathogenesis of spinal cord injury (SCI) via promoting inflammation. Recently, we have reported that trehalose suppresses inflammatory responses following SCI. Therefore, we investigated the effe...

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Detalles Bibliográficos
Autores principales: Mirzaie, Masoumeh, Karimi, Mehrnaz, Fallah, Hossein, Khaksari, Mohammad, Nazari-Robati, Mahdieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Babol University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134419/
https://www.ncbi.nlm.nih.gov/pubmed/30234068
http://dx.doi.org/10.22088/IJMCM.BUMS.7.1.8