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Nogo-B receptor increases the resistance to tamoxifen in estrogen receptor-positive breast cancer cells

BACKGROUNDS: Tamoxifen is typically used to treat patients with estrogen receptor alpha (ERα)-positive breast cancer. However, 30% of these patients gain acquired resistance to tamoxifen during or after tamoxifen treatment. As a Ras modulator, Nogo-B receptor (NgBR) is required for tumorigenesis thr...

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Detalles Bibliográficos
Autores principales: Gao, Pin, Wang, Xiang, Jin, Ying, Hu, Wenquan, Duan, Yajun, Shi, Aiping, Du, Ye, Song, Dong, Yang, Ming, Li, Sijie, Han, Bing, Zhao, Gang, Zhang, Hongquan, Fan, Zhimin, Miao, Qing Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134690/
https://www.ncbi.nlm.nih.gov/pubmed/30208932
http://dx.doi.org/10.1186/s13058-018-1028-5