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Clinical benefit and radiological response with BRAF inhibitor in a patient with recurrent ameloblastoma harboring V600E mutation

BACKGROUND: Ameloblastoma is a slow-growing neoplasm of the jaw, for which the standard treatment is surgical removal of the lesion with high recurrence rates and elevated morbidity. Systemic therapy is not established in the literature. CASE PRESENTATION: We present a case of a 29-year-old woman di...

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Detalles Bibliográficos
Autores principales: Fernandes, Gustavo S., Girardi, Daniel M., Bernardes, João Paulo G., Fonseca, Felipe P., Fregnani, Eduardo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134697/
https://www.ncbi.nlm.nih.gov/pubmed/30208863
http://dx.doi.org/10.1186/s12885-018-4802-y