Cargando…

Expression of selected genes isolated from whole blood, liver and obex in lambs with experimental classical scrapie and healthy controls, showing a systemic innate immune response at the clinical end-stage

BACKGROUND: Incubation period, disease progression, pathology and clinical presentation of classical scrapie in sheep are highly dependent on PRNP genotype, time and route of inoculation and prion strain. Our experimental model with pre-colostrum inoculation of homozygous VRQ lambs has shown to be a...

Descripción completa

Detalles Bibliográficos
Autores principales: Meling, Siv, Skovgaard, Kerstin, Bårdsen, Kjetil, Helweg Heegaard, Peter Mikael, Ulvund, Martha J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134718/
https://www.ncbi.nlm.nih.gov/pubmed/30208891
http://dx.doi.org/10.1186/s12917-018-1607-9